For each of the functional analysis selected to be performed, the same descriptive statistics as in the Path values case are shown:

• GO terms/Uniprot keywords values: You can download the matrix of function values by clicking on GO terms values or Uniprot keywords values.
• Heatmap: A heatmap is a graphical representation of the values of a matrix. A not-supervised clustering is performed on the data per columns (samples). A good separation between the two colors of the upper bar of the heatmap indicates that the differences between the two groups are big enough to discriminate between them.
• PCA: A Principal Components Analysis is performed in order to see if the matrix contains information enough to separate between the two groups.
• Path significance: Ordered table of the functions significance. More significant terms are displayed in the upper part of the table. For each functional term, the following information is shown:
  • path/term: Name of the function.
  • UP/DOWN: Up when the function is up-regulated in the disease case, DOWN otherwise.
  • statistic: Statistic of the of the statistic test.
  • p.value: P-value of the statistic test.
  • FDRp.value: Adjusted p-value of the statistic test using the FDR method.