Metabolizer

The design data panel allows you to choose the kind of experiment you want to perform. You can choose between three kinds of experimental design:

• Two group comparison: The comparison is performed between the two groups described in the experimental design file. The experimental design file must include two columns: the first one with the names of the samples, the second one with the class to which each sample belongs.

• Correlation with continuous variable: A correlation is performed between the values of each path along the samples and the continuous variable introduced. The experimental design file must include two columns: the first one with the names of the samples, the second one with the value of the variable for each one of the samples.

• Mutation effect: The comparison is performed between the expression matrix without considering the mutations, and the expression matrix resulting from integrating the information about the mutations. No experimental design file is needed. This option is only available from Differential signaling tool.